Bilirubin is a pigment made from the hemoglobin in the red cell. The red cell has a fixed life span and is destroyed every day. At this point, the hemoglobin will decompose into the heme (haem) and heme. Heme to biliverdin in the NADPH and H ions. The trivalent Fe ion and CO, generated in NADPH and bilirubin biliverdin H ions. Heme reproduces tissue protein, and bilirubin plays an important role in the metabolism of human body. The normal value of bilirubin is an important basis for determining normal / abnormal liver function.
The reasons for the high total bilirubin are:
(1): when hemolytic disease, neonatal jaundice or blood transfusion mistake, it will lead to massive destruction of red blood cells, resulting in a high level of indirect bilirubin in blood, resulting in a high level of total bilirubin.
(two) when liver and extrahepatic obstructive jaundice, pancreatic head cancer, capillary cholangio hepatitis and other biliary stasis syndrome and other diseases, biliary tract obstruction, excretion of bile damage, leading to direct bilirubin is high, resulting in high total bilirubin.
(three): when had hepatitis disease, such as acute icteric hepatitis, acute icteric hepatitis, chronic active hepatitis, liver cirrhosis, toxic hepatitis, the pathological changes of liver cells, cannot be transformed into direct bilirubin and indirect bilirubin, direct bilirubin and indirect bilirubin result are high, resulting in high total bilirubin.
If you drink very frequently, it's better to drink less or not. In time, further examination and definite diagnosis.