Who can tell me What are the symptoms of hepatitis B?

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asked in Internal Medicine by CARRIE
What are the symptoms of hepatitis B?

5 Answers

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answered by ADRIENNE
1. Symptoms
Limb weakness, mental concentration, easy fatigue, difficulty lassitude, loss of appetite, nausea and vomiting, and with fever, listlessness, abdominal pain and indigestion. In addition to the increase of bilirubin in patients with hepatitis B, there will be jaundice symptoms, the symptoms of yellow skin, yellow eyes and yellow urine. There is often no symptoms, and the condition is not found.
Two, signs
1. Acute hepatitis B
It may be characterized by acute jaundice hepatitis and acute non jaundice hepatitis. Acute jaundice type may have typical clinical manifestations, such as fever, fatigue, anorexia, nausea, vomiting, abdominal distension, tired of the oil, liver pain, yellow urine Rucha water and so on, some patients even had the stool pale, skin itching, liver area tenderness and percussion pain, acute non icteric more occult, mild symptoms, like a mild fatigue, anorexia, nausea and discomfort, rapid recovery, often medical laboratory was found. Acute hepatitis B symptoms, the patient must pay attention to check and timely treatment, avoid illness chronicity development.
2. Chronic hepatitis B
According to the condition of the disease, it can be divided into three kinds of light, medium and heavy.
Mild, mild, repeated fatigue, dizziness, appetite decrease, tired of the oil, yellow urine, liver discomfort, poor sleep, liver slightly light tenderness, may have mild splenomegaly. Symptoms and signs were absent in some cases. Only 1 or 2 mild abnormalities of liver function were found.
Moderate: symptoms, signs, laboratory tests are between mild and severe.
重度:有明显或持续的肝炎症状,如乏力、纳差、腹胀、尿黄、便溏等,伴肝病面容、肝掌、蜘蛛痣、脾大,ALT和(或)天冬氨酸氨基转移酶(AST)反复或持续升高,白蛋白降低、丙种球蛋白明显升高。
3. Severe hepatitis
Extreme weakness, severe gastrointestinal symptoms, neurologic, mental symptoms (lethargy, character change, restlessness, coma, etc.)
4. Cholestatic hepatitis
Jaundice continues to not retreat for more than 3 weeks, known as cholestatic hepatitis. A special clinical type mainly characterized by intrahepatic cholestasis is also known as capillary cholangitis type hepatitis. Chronic cholestatic hepatitis often occurs on the basis of liver cirrhosis, which is not easy to fade, often accompanied by γ - glutamyl transpeptidase, alkaline phosphatase, and total bile acid.
5. Hepatitis cirrhosis
(1) according to the liver inflammation, it is divided into active and static type two.
Active cirrhosis: symptoms of chronic hepatitis, fatigue and digestive tract symptoms, increased ALT, jaundice, and albumin decline.
Static liver cirrhosis: no liver inflammatory activity, mild symptoms or no specificity, can have the above signs.
(2) according to the pathological and clinical manifestations of liver tissue, it is divided into compensatory cirrhosis and decompensated cirrhosis.
Compensatory cirrhosis: ALB = 35g/L, TBil < 35μ mol/L, PTA > 60%. There is a portal hypertension, but there is no ascites, hepatic encephalopathy or upper gastrointestinal bleeding.
Decompensated cirrhosis: middle and late stage cirrhosis, with obvious liver dysfunction and decompensation signs, such as ALB < 35g/L, albumin / globulin (A/G) < 1, TBil > 35μ mol/L, PTA < 60%. There can be obvious varicose or ruptured bleeding of the esophagus and the fundus of the stomach caused by ascites, hepatic encephalopathy or portal hypertension.
Three. Diagnostic criteria
There are three methods for the diagnosis of hepatitis B: the antigen test of the virus, the antibody test of the human body and the deoxyribonucleic acid test of the virus.
Antigen: the antigen of hepatitis B tested is two: hepatitis B surface antigen (HBs-Ag) and hepatitis B virus e antigen (HBe-Ag). If these two antigens exist, it is indicated that the patient is still sick. In the best case, the patient has only HBs-Ag and no symptoms, which indicates that the patient is healthy, but with the virus. If the patient has HBe-Ag in the body, his infection is very high, but even if only HBs-Ag patients can still be infected with others.
Antibodies: the antibodies to be tested for hepatitis B have two: Anti-HBc-IgM and Anti-HBcIgG, which are signs of recovery, and they will appear after vaccination. Anti-HBc-IgM is a sign of acute hepatitis B, and Anti-HBcIgG occurs at the end of acute hepatitis B or when the patient has just recovered. To test these antibodies that have improved conditions in patients with chronic hepatitis B, and appeal to drop.
Deoxyribonucleic acid: the old technology is used to test the DNA of hepatitis B virus. It mainly determines the condition of the disease in uncertain condition, and determines the infectivity of the patient. In modern medicine, this data is also used to diagnose and observe chronic hepatitis B. The number of virus deoxyribonucleic acid in the blood indicates that the disease is not aggravated, and the number of the disease is much more indicating the deterioration of the disease.
1. auxiliary examination
Liver function examination
It includes bilirubin, thymol turbidity test, AST, ALT, A/G, prothrombin time, serum protein electrophoresis, etc.
2. specific serological examination
It includes HBsAg, anti -HBs, HBeAg, anti -HBe, anti -HBc, and anti -HBcIgM. Conditions can be detected for HBV-DNA, DNA-p, Pre-S1, Pre-S2 and so on. In situ hybridization was used to detect HBV-DNA in the liver.
Four. Classification
1. acute hepatitis B
Before the symptoms appear, the virus may have been latent for a few months. During this period, the contagion is very high, and the patient may unconsciously pass on to the person who is in contact with him. The early symptoms caused by hepatitis B are not very obvious, just like a bad cold, including mild fever, exhaustion, muscle pain, headache, loss of appetite, and aversion to smoking. Afterwards, nausea and vomiting, upper abdominal discomfort and sore pain, constipation or diarrhea will happen. As the course becomes worse, the skin will turn yellow and white, the color of urine
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answered by LULA
1. symptoms: hepatitis B patients often feel tired, fatigue, no spirit, the reason, in addition to pathological causes may be caused by the damage of liver function, but also may be due to lower energy consumption and increase the morbidity, reduce consumption, digestion and absorption of food, nutrient intake can not meet the needs of the body lead. On the other hand, hepatitis B infection is not only physical pain, but also mental and mental stress from external mental and psychological pressure. It can also cause systemic symptoms.
2. digestive tract symptoms: the liver is an important digestive organ, and the bile secreted by the liver is necessary for food digestion. In the case of liver disease, the secretion of bile is affected, which affects the digestion and absorption of food. There is no appetite, nausea, oil, upper abdominal discomfort, abdominal distention and other symptoms of hepatitis B.
3. jaundice: the liver is the key of bilirubin metabolism. When the disease is heavier, the bilirubin metabolism dysfunction of the liver leads to the increase of bilirubin concentration in the blood, resulting in jaundice. When the concentration of bilirubin in the blood is increased, the bilirubin is discharged from the urine to make the urine color darker. It is the earliest manifestation of jaundice. It should be noted that too little drinking water or some drugs will also cause urine yellow phenomenon, should pay attention to the difference. When the concentration of bilirubin in the blood continues to increase, it can cause jaundice in the eyes and skin, and severe icterus can cause itching of the skin.
4. pain in the liver area: the pain in the liver is one of the main symptoms of hepatitis B. Hepatitis B generally do not have severe pain, when inflammation of the liver enlargement, liver capsule tension, pain nerve stimulation, can cause liver pain, stuffy pain, discomfort, etc.. If the pain is more severe, it should be suspected of being accompanied by other diseases.
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answered by ALEXANDRA
The symptoms of hepatitis B are many, 1. of the whole body often feel tired, easy to fatigue, with mild fever and so on. Insomnia, dream and so on may be related to this. 2. gastrointestinal manifestations of hepatitis, abnormal liver function, bile secretion, often loss of appetite, nausea, tired of the oil, abdominal discomfort, abdominal distension etc.. 3. when the condition of jaundice is heavier, the liver function is impaired, the intake of bilirubin, the binding, secretion and excretion of bilirubin, and the concentration of bilirubin in the blood is increased. Bilirubin is excreted from urine and the color of urine turns yellow. It is the earliest manifestation of jaundice. The concentration of bilirubin in the blood continues to increase, which can cause yellow dye in the eyes and skin. Due to the barrier of bile acid excretion, the concentration of bile acid in the blood increases, too much bile acid is deposited on the skin, stimulating the end of the nerve and causing itching. Chronic hepatitis B in the 4. liver area has no severe pain in general. Some patients may have the right upper quadrant, right hypochondrium discomfort, pain, tenderness and percussion pain. If the pain in the liver is severe, we should pay attention to the possibility of biliary disease, liver cancer and gastrointestinal disease, so as not to be misdiagnosed. 5. hepatosplenomegaly due to inflammation, hyperemia, edema, cholestasis, patients often have swelling of the liver. In the late period, a large number of hepatocytes were destroyed, fibrous tissue contracted and the liver could be reduced. In the early stage of acute or chronic hepatitis, there is no obvious swelling in the spleen. When the portal hypertension is high, the spleen is congested, which can cause the splenomegaly. 6. the expression of chronic hepatitis B, especially in the liver cirrhosis, is dark and dark, which is called liver disease. Hand, hypothenar had hyperemia called liver palms. A cluster of capillaries, such as spiders, called spider nevus on the skin, and other parts of the skin. Male can appear erectile dysfunction, symmetric or asymmetric breast hyperplasia, swelling and breast development, and even misdiagnosed as breast cancer. Women can have menstrual disorders, amenorrhea, loss of sexual desire and so on. This may be related to the decrease of liver function, the decrease of estrogen inactivation and the increase of estrogen in the body. 7., liver fibrosis, chronic hepatitis B inflammation is not recovered for a long time, recurrent attacks, intrahepatic fibrous connective tissue hyperplasia, and its degradation activity is relatively or absolutely insufficient, a large number of extracellular matrix deposition to form liver fibrosis. If liver fibrosis is associated with the destruction of the hepatic lobule structure (the liver regeneration nodule), it is called liver cirrhosis. It is difficult to separate the two in clinical, and the chronic liver disease from liver fibrosis to liver cirrhosis is a continuous development process. Attention should be paid to hepatitis B. 1., if the liver function (serum aminotransferase) is normal for more than 3 months, it can gradually engage in light work, and then gradually increase the workload until the original work is resumed. 2., chronic hepatitis B patients have low immune function, and are easily infected by various viruses, bacteria and other pathogenic factors, which will make the disease that has already been stationary or tends to heal and reactivate and deteriorate. The patients in daily life, personal hygiene and other aspects should be cautious, to exercise, change at any time to change clothes according to the weather temperature, to prevent colds and infections. 3. the patients with chronic hepatitis B should eat food containing high quality protein, pay attention to the supplement of high fiber, high vitamin food and selenium, and low fat and proper sugar diet. Do not drink alcohol, eat spicy, fried food; bogey sweets; avoid blind tonic, so as not to increase the burden of liver or liver damage. 4. the liver function, two to half of hepatitis B, alpha fetoprotein and B ultrasound can be reviewed regularly in patients with chronic hepatitis B.
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answered by MELODY
The main symptoms that may occur in the early stage of hepatitis B are the following:
1, loss of appetite, nausea, tired of the oil: This is the majority of hepatitis B patients have symptoms, especially jaundice hepatitis patients is more serious, because of suffering from hepatitis, due to hepatitis B virus induced liver cells damage, bile secretion function decreased, thus affecting the digestion of fat, so tired of oil food.
2, fatigue weakness: This is one of the early manifestations of hepatitis B disease. The light is not love, but because the patient completely bedridden, loss of appetite, disorder of digestion and absorption, leading to lack of human energy; the second is due to the virus cause liver cell damage, liver glycogen storage and reduce manufacturing; and lack of vitamins, electrolyte disorder and liver cell damage caused by reduced blood cholinesterase, effect of nerve, muscle function.
3, yellow urine Rucha: jaundice hepatitis patients have symptoms of yellow urine. At first, the color of the urine is pale yellow, deepened day by day, as thick as tea or bean oil, and then the skin and the sclera are yellow. Hepatitis B virus causes liver cell destruction, affects bilirubin metabolism, makes bilirubin increase into blood, and excretion in urine increases more frequently than usual. Therefore, urine color deepens and urine color is yellow. It indicates that the heavier the liver cell is, the better the condition is, and the urine color gradually returns to normal.
4: fever, acute icteric hepatitis B early fever, in 37.538.5 degrees, high fever is rare, usually lasts for 3-5 days, without jaundice hepatitis fever is far lower than that of hepatitis jaundice. Many patients have fever accompanied by discomfort and loss of appetite, and they are mistaken for a cold.
5, liver area pain: hepatitis patients often complain about liver pain, involving the right upper abdomen or right back, varying degrees of pain, some of them are distending pain, dull pain or pinprick pain. They are aggravated by activity and different time. Sometimes, when they lie on the left side, they have less pain.
6. A few cases of severe hepatitis have abdominal distention, oliguria and bleeding tendency.
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answered by WHITNEY
The general expression of the patient is often tired, easy to fatigue, and can be accompanied by mild fever. Insomnia, dream and so on may be related to this. 2. gastrointestinal manifestations of hepatitis, abnormal liver function, bile secretion, often loss of appetite, nausea, tired of the oil, abdominal discomfort, abdominal distension etc.. 3. when the condition of jaundice is heavier, the liver function is impaired, the intake of bilirubin, the binding, secretion and excretion of bilirubin, and the concentration of bilirubin in the blood is increased. Bilirubin is excreted from urine and the color of urine turns yellow. It is the earliest manifestation of jaundice. The concentration of bilirubin in the blood continues to increase, which can cause yellow dye in the eyes and skin. Due to the barrier of bile acid excretion, the concentration of bile acid in the blood increases, too much bile acid is deposited on the skin, stimulating the end of the nerve and causing itching. Chronic hepatitis B in the 4. liver area has no severe pain in general. Some patients may have the right upper quadrant, right hypochondrium discomfort, pain, tenderness and percussion pain. If the pain in the liver is severe, we should pay attention to the possibility of biliary disease, liver cancer and gastrointestinal disease, so as not to be misdiagnosed.
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